Board of Directors
Phillip Frost, M.D.
Dr. Frost became the CEO and Chairman of OPKO Health, Inc. on March 27, 2007, following the consummation of the merger of Acuity Pharmaceuticals, Inc., Froptix Corporation, and eXegenics, Inc. Dr. Frost was named the Chairman of the Board of Teva Pharmaceutical Industries, Ltd. in March 2010, having served as Teva’s Vice Chairman since January 2006, Teva’s acquisition of IVAX Corporation. Dr. Frost had served as Chairman of the Board of Directors and Chief Executive Officer of IVAX Corporation since 1987. He was Chairman of the Department of Dermatology at Mt. Sinai Medical Center of Greater Miami, Miami Beach, Florida from 1972 to 1986. He was also Chairman of the Board of Directors of Key Pharmaceuticals, Inc. from 1972 until the acquisition of Key Pharmaceuticals by Schering Plough Corporation in 1986. In July 2006, Dr. Frost was also named Chairman of the Board of Ladenburg Thalmann Financial Services Inc., an investment banking, asset management, and securities brokerage firm providing services through its principal operating subsidiary, Ladenburg Thalmann & Co., Inc. He has been a director of Ladenburg Thalmann from 2001 until 2002, and again since 2004. Dr. Frost also serves as Chairman of the Board of Directors of PROLOR Biotech, Inc., a development-stage biopharmaceutical company. He serves as a member of the Board of Trustees of the University of Miami and as a Trustee of the Scripps Research Institute, the Miami Jewish Home for the Aged, and the Mount Sinai Medical Center. Dr. Frost is also a director of Castle Brands, a developer and marketer of premium brand spirits. Dr. Frost previously served as a director for Continucare Corporation, Northrop Grumman Corp., Ideation Acquisition Corp., Protalix Bio Therapeutics, Inc., and SafeStitch Medical Inc. He also served as Governor and Co-Vice-Chairman of the American Stock Exchange.
Jane H. Hsiao, Ph.D., M.B.A.
Dr. Hsiao has served as Vice Chairman and Chief Technical Officer of the Company since May 2007. She served as the Vice Chairman-Technical Affairs of IVAX from 1995 to January 2006, in addition to serving as Chairman, Chief Executive Officer and President of IVAX Animal Health, IVAX’s veterinary products subsidiary, from 1998 to 2006. Dr. Hsiao has served as Chairman of the Board of Safestitch Medical, Inc. and of Non-Invasive Monitoring Systems, Inc., both medical device companies, since September 2007 and October 2008, respectively. She was named Interim Chief Executive Officer of Non-Invasive Monitoring Systems, Inc. in February 2012. Dr. Hsiao is also a director of PROLOR Biotech, Inc., a development-stage biopharmaceutical company, Sorrento Therapeutics, Inc., a development-stage biopharmaceutical company, and Neovasc, Inc., a company developing and marketing medical specialty vascular devices. Dr. Hsiao also previously served as a director for Protalix BioTherapeutics, Inc.
Steven D. Rubin
Mr. Rubin has served as Executive Vice President – Administration since May 2007 and as a director of the Company since February 2007. He served as the Senior Vice President, General Counsel and Secretary of IVAX from August 2001 until September 2006. He currently serves on the board of directors of Dreams, Inc., a vertically integrated sports licensing and products company; Safestitch Medical, Inc., a medical device company; Searchmedia Holdings, Ltd, a leading nationwide multi-platform media company and one of the largest operators of integrated outdoor billboard and in-elevator advertising networks in China; PROLOR Biotech, Inc., a development stage biopharmaceutical company; Kidville, Inc., which operates large, upscale facilities catering to newborns through five-year-old children and their families and offers a wide range of developmental classes for the children involved; Non-Invasive Monitoring Systems, Inc., a medical device company; Tiger X Medical, Inc., previously an early-stage orthopedic medical device company specializing in designing, developing, and marketing reconstructive joint devices and spinal surgical devices; Castle Brands, Inc., a developer and marketer of premium brand spirits; and Neovasc, Inc., a company developing and marketing medical specialty vascular devices.
Robert A. Baron
Mr. Baron has served as a director of the Company since 2003. He is also currently a director of Andover Medical, Inc., a durable medical equipment distributor. Prior to that, he was president of Cash City, Inc., a payday advance and check cashing business, from 1999 to 2003. From 1997 to 1999, Mr. Baron was the president of East Coast operations for CSS/TSC, Inc., a distributor of blank t-shirts, fleece, and accessories and a subsidiary of Tultex, Inc. Mr. Baron previously served as a director of Hemobiotech, Inc. and Nanosensors, Inc.
Thomas E. Beier
Mr. Beier has served as a director of the Company since January 2008. Previously, he was Senior Vice President of Finance and Chief Financial Officer of IVAX from October 1997 until August 2007. From December 1996 until October 1997, he served as Vice President – Finance for IVAX. Before joining IVAX, Mr. Beier served as Executive Vice President and Chief Financial Officer of Intercontinental Bank. He also previously served as a director of Ideation Acquisition Corp.
Mr. Kolosov was elected to serve as a director of the Company at the 2012 Annual Meeting of Stockholders. An attorney, Mr. Kolosov presently serves as the Vice President, Chief of Staff, and Member of the Management Board of the Skolkovo Foundation, a nonprofit organization in Russia charged by Russian President Dmitry Medvedev with creating a new science and technology city in the Moscow suburb of Skolkovo. Skolkovo comprises a university, research institutions, centers of collective usage, a business incubator, a technology transfer and commercialization office, corporate offices, and research and development centers, in addition to residential space and social infrastructure. From 2002 until 2010, when he joined the Skolkovo Foundation, Mr. Kolosov served in various positions, including Executive Secretary of the Board of Directors and Head of Shareholder Relations, and Advisor to the Executive Chairman of the Board, of TNK-BP, a joint venture between BP plc and the Alfa-Access-Renova consortium, among the ten largest private oil companies in the world.
Richard A. Lerner, M.D.
Dr. Lerner has served as a director of the Company since March 2007. Dr. Lerner served as President of The Scripps Research Institute, a private, non-profit biomedical research organization, from 1986 until 2011. He is currently serving as an institute professor there. Dr. Lerner is a member of numerous scientific associations, including the National Academy of Science and the Royal Swedish Academy of Sciences. He also serves as a director of Kraft Foods, Inc. and Sequenom, Inc., a life sciences company. He is also on the board of directors for Intra-Cellular Therapies, a privately held biotechnology company. He previously served as a director of privately held biotechnology company Xencor, and on the Siemens’ Advisory Board for Molecular Medicine of Siemens AG.
John A. Paganelli
Mr. Paganelli has served as a director of the Company since December 2003. He served as the Company’s Interim Chief Executive Officer and Secretary from June 29, 2005 through March 27, 2007, and as Chairman of the Company’s Board of Directors from December 2003 through March 27, 2007. Mr. Paganelli has previously served as President and Chief Executive Officer of Transamerica Life Insurance Company of New York from 1992 to 1997. Since 1987, he has also been a partner in RFG Associates, a financial planning organization. Mr. Paganelli is the Managing Partner of investment company Pharos Systems Partners, LLC, and he is also Chairman of the Board of software company Pharos Systems International. He was Vice President and Executive Vice President of PEG Capital Management, an investment advisory organization, from 1987 until 2000. From 1980 to January 2003, Mr. Paganelli was an officer and director-stockholder of Mike Barnard Chevrolet, Inc., an automobile dealership. He also serves as a director of Western New York Energy, LLC and is on the Board of Trustees of Paul Smith’s College. Mr. Paganelli previously served on the Board of Managers of Bridge Financial Services, LLC.
Richard C. Pfenniger, Jr.
Mr. Pfenniger has served as a director of the Company since January 2008. He served as Chief Executive Officer and President for Continucare Corporation, a provider of primary care physician and practice management services, from October 2003 until October 2011. He previously served as Chairman of the Board of Directors of Continucare from September 2002 until October 2011. Mr. Pfenniger also served as the Chief Executive Officer and Vice Chairman of Whitman Education Group, Inc. from 1997 through June 2003. Prior to joining Whitman, he served as the Chief Operating Officer of IVAX from 1994 to 1997, and, from 1989 to 1994, he served as the Senior Vice President – Legal Affairs and General Counsel of IVAX Corporation. Mr. Pfenniger currently serves as a director of GP Strategies Corporation, a corporate education and training company, and of SafeStitch Medical, Inc., a medical device company.
Alice Lin-Tsing Yu, M.D., Ph.D.
Dr. Yu was appointed to the Company’s Board of Directors in April 2009. Since 2003, she has served as Distinguished Research Fellow and Associate Director at the Genomics Research Center, Academia Sinica, in Taiwan. She has also served as a Professor of Pediatrics for both the National Taiwan University and the University of California in San Diego, since 2004 and 1994, respectively. Previously, she was the Chief of Pediatric Hematology Oncology at the University of California in San Diego. Dr. Yu has also served in several government-appointed positions and is a member of numerous scientific committees and associations.