Annual report pursuant to Section 13 and 15(d)

Composition of Certain Financial Statement Captions - Changes in Goodwill (Detail)

v3.10.0.1
Composition of Certain Financial Statement Captions - Changes in Goodwill (Detail) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Goodwill [Roll Forward]      
Beginning balance $ 717,099,000 $ 704,603,000  
Goodwill impairment (11,698,000) 0 $ 0
Foreign exchange and other (5,208,000) 12,496,000  
Ending balance 700,193,000 717,099,000 704,603,000
BioReference Laboratories, Inc.      
Goodwill [Roll Forward]      
Ending balance 401,800,000    
Pharmaceutical | CURNA      
Goodwill [Roll Forward]      
Beginning balance 4,827,000 4,827,000  
Goodwill impairment    
Foreign exchange and other 0 0  
Ending balance 4,827,000 4,827,000 4,827,000
Pharmaceutical | EirGen Pharma Limited      
Goodwill [Roll Forward]      
Beginning balance 89,226,000 78,358,000  
Goodwill impairment    
Foreign exchange and other (3,981,000) 10,868,000  
Ending balance 85,245,000 89,226,000 78,358,000
Pharmaceutical | FineTech      
Goodwill [Roll Forward]      
Beginning balance 11,698,000 11,698,000  
Goodwill impairment (11,698,000)    
Foreign exchange and other 0 0  
Ending balance 0 11,698,000 11,698,000
Pharmaceutical | OPKO Biologics      
Goodwill [Roll Forward]      
Beginning balance 139,784,000 139,784,000  
Goodwill impairment    
Foreign exchange and other 0 0  
Ending balance 139,784,000 139,784,000 139,784,000
Pharmaceutical | OPKO Chile      
Goodwill [Roll Forward]      
Beginning balance 5,203,000 4,785,000  
Goodwill impairment    
Foreign exchange and other (589,000) 418,000  
Ending balance 4,614,000 5,203,000 4,785,000
Pharmaceutical | OPKO Health Europe      
Goodwill [Roll Forward]      
Beginning balance 7,898,000 6,936,000  
Goodwill impairment    
Foreign exchange and other (352,000) 962,000  
Ending balance 7,546,000 7,898,000 6,936,000
Pharmaceutical | OPKO Renal      
Goodwill [Roll Forward]      
Beginning balance 2,069,000 2,069,000  
Goodwill impairment    
Foreign exchange and other 0 0  
Ending balance 2,069,000 2,069,000 2,069,000
Pharmaceutical | Transition Therapeutics, Inc.      
Goodwill [Roll Forward]      
Beginning balance 3,608,000 3,360,000  
Goodwill impairment    
Foreign exchange and other (286,000) 248,000  
Ending balance 3,322,000 3,608,000 3,360,000
Diagnostics | BioReference Laboratories, Inc.      
Goodwill [Roll Forward]      
Beginning balance 401,821,000 401,821,000  
Goodwill impairment    
Foreign exchange and other 0 0  
Ending balance 401,821,000 401,821,000 401,821,000
Diagnostics | OPKO Diagnostics      
Goodwill [Roll Forward]      
Beginning balance 17,977,000 17,977,000  
Goodwill impairment    
Foreign exchange and other 0 0  
Ending balance 17,977,000 17,977,000 17,977,000
Diagnostics | OPKO Lab      
Goodwill [Roll Forward]      
Beginning balance 32,988,000 32,988,000  
Goodwill impairment    
Foreign exchange and other 0 0  
Ending balance $ 32,988,000 $ 32,988,000 $ 32,988,000