Annual report pursuant to Section 13 and 15(d)

Debt - Narrative (Details)

v3.10.0.1
Debt - Narrative (Details)
1 Months Ended 12 Months Ended 48 Months Ended
Dec. 22, 2017
USD ($)
Aug. 07, 2017
USD ($)
Mar. 17, 2017
USD ($)
Nov. 05, 2015
USD ($)
Feb. 28, 2018
USD ($)
$ / shares
Jan. 31, 2013
USD ($)
d
$ / shares
Rate
Dec. 31, 2018
USD ($)
institution
Rate
Dec. 31, 2017
USD ($)
Rate
Dec. 31, 2016
USD ($)
Rate
Dec. 31, 2016
USD ($)
shares
Feb. 28, 2019
Feb. 01, 2019
USD ($)
Nov. 08, 2018
USD ($)
Debt Instrument [Line Items]                          
Credit line capacity             $ 197,189,000            
Gain (loss) on embedded derivative             0            
Goodwill             $ 700,193,000 $ 717,099,000 $ 704,603,000 $ 704,603,000      
Number of financial institutions | institution             11            
BioReference Laboratories, Inc.                          
Debt Instrument [Line Items]                          
Net assets             $ 916,400,000            
Goodwill             401,800,000            
Intangible assets             $ 405,300,000            
OPKO Health Europe                          
Debt Instrument [Line Items]                          
Weighted average interest rate             2.10% 3.00%          
Minimum | OPKO Health Europe                          
Debt Instrument [Line Items]                          
Variable interest rates             1.00%            
Maximum | OPKO Health Europe                          
Debt Instrument [Line Items]                          
Variable interest rates             6.30%            
Notes | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Interest rate of notes payable           3.00% 3.00% 3.00% 3.00% 3.00%      
Debt face amount           $ 175,000,000.0              
Conversion price (in dollars per share) | $ / shares           $ 7.07              
Equivalent redemption price           100.00%              
Conversion ratio | Rate           14.14827% 14.14827% 14.14827% 14.14827%        
Convertible debt, threshold percentage of stock price trigger           130.00%              
Estimated credit spread | Rate             7.61% 7.65% 11.42%        
Notes | Notes Due February 1, 2033 | Minimum                          
Debt Instrument [Line Items]                          
Threshold trading days | d           20              
Notes | Notes Due February 1, 2033 | Maximum                          
Debt Instrument [Line Items]                          
Number of consecutive trading days applicable conversion price | d           30              
Notes | Notes Due February 1, 2033 | On or after February 1, 2017 and before February 1, 2019                          
Debt Instrument [Line Items]                          
Equivalent redemption price           100.00%              
Convertible Debt | 5% Convertible Notes                          
Debt Instrument [Line Items]                          
Interest rate of notes payable         5.00%                
Debt face amount         $ 55,000,000.0                
Note maturity term         5 years                
Par value of shares issued upon conversion (in dollars per share) | $ / shares         $ 0.01                
Conversion price (in dollars per share) | $ / shares         $ 5.00                
Conversion notice threshold minimum         30 days                
Conversion notice threshold maximum         60 days                
Convertible Debt | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Convertible notes, conversion                   $ 143,200,000      
Line of Credit                          
Debt Instrument [Line Items]                          
Weighted average interest rate             4.70% 4.20%          
Equity securities | Convertible Debt | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Convertible debt, stock issued from conversion (in shares) | shares                   21,539,873      
Line of Credit | Unsecured Debt                          
Debt Instrument [Line Items]                          
Credit line capacity                         $ 60,000,000
Interest rate of notes payable                         10.00%
Long term debt             $ 0            
Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Credit line capacity       $ 175,000,000.0                  
Higher borrowing capacity option       $ 275,000,000.0                  
Remaining borrowing capacity             $ 2,000,000.0            
Commitment fee percentage       0.50%                  
Intercompany loan maximum borrowing capacity $ 45,000,000.0 $ 35,000,000.0 $ 55,000,000.0                    
Bridge Loan | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Credit line capacity       $ 20,000,000.0                  
Letter of Credit | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Credit line capacity       $ 20,000,000.0                  
LIBOR | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Estimated credit spread       2.50%                  
LIBOR, First 12 Months | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Estimated credit spread       0.35%                  
LIBOR, thereafter | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Estimated credit spread       0.50%                  
LIBOR, First 12 Months, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Estimated credit spread       1.35%                  
LIBOR, Thereafter, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Estimated credit spread       1.50%                  
Subsequent Event | Notes | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Debt repurchase amount                       $ 28,800,000  
Subsequent Event | Convertible Debt                          
Debt Instrument [Line Items]                          
Interest rate of notes payable                     4.50%