Annual report pursuant to Section 13 and 15(d)

Equity-Based Compensation - Narrative (Details)

v3.10.0.1
Equity-Based Compensation - Narrative (Details)
12 Months Ended
Dec. 31, 2018
USD ($)
Plan
$ / shares
shares
Dec. 31, 2017
USD ($)
$ / shares
Dec. 31, 2016
USD ($)
$ / shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Number of equity-based incentive compensation plans | Plan 6    
Expiration period 10 years    
Number of modigene plans | Plan 2    
Vesting period 5 years    
Excess tax benefits $ 0 $ 0 $ 0
Unrecognized compensation cost $ 24,600,000    
Weighted-average expected period for recognition 1 year 5 months 23 days    
Expected dividend yield 0.00% 0.00% 0.00%
Common stock shares reserved for issuance (in shares) | shares 26,668,368    
Intrinsic value of stock options exercised $ 500,000 $ 6,400,000 $ 9,900,000
Weighted average grant date fair value of stock options granted (in dollars per share) | $ / shares $ 2.08 $ 4.50 $ 4.78
Fair value of stock options vested $ 25,800,000 $ 34,000,000 $ 30,200,000
Selling, General and Administrative Expenses      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Equity based compensation expense 14,700,000 21,200,000 33,400,000
Research and Development Expense      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Equity based compensation expense 4,200,000 5,100,000 7,500,000
Cost of Revenue      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Equity based compensation expense 2,800,000 2,000,000.0 1,800,000
Continuing Operations      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Equity based compensation expense $ 21,800,000 $ 28,300,000 $ 42,700,000
Minimum | 2007 Equity Incentive Plan      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expiration period 7 years    
Maximum | 2007 Equity Incentive Plan      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expiration period 10 years    
Employee Stock Option      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Vesting period 4 years    
Non-employee Director | Employee Stock Option      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Vesting period 1 year