Quarterly report pursuant to Section 13 or 15(d)

Debt - Narrative (Details)

v3.19.1
Debt - Narrative (Details)
1 Months Ended 3 Months Ended 48 Months Ended
Feb. 20, 2019
USD ($)
Jan. 30, 2013
USD ($)
Feb. 28, 2019
USD ($)
d
$ / shares
shares
Feb. 28, 2018
USD ($)
$ / shares
Nov. 30, 2015
USD ($)
Jan. 31, 2013
Mar. 31, 2019
USD ($)
institution
shares
Mar. 31, 2018
USD ($)
Dec. 31, 2016
USD ($)
shares
Feb. 01, 2019
USD ($)
Dec. 31, 2018
USD ($)
institution
Nov. 08, 2018
USD ($)
Debt Instrument [Line Items]                        
Repayments of lines of credit             $ 35,313,000 $ 12,420,000        
Credit line capacity             197,171,000          
Goodwill             $ 698,522,000       $ 700,193,000  
Number of financial institutions | institution             11       11  
BioReference                        
Debt Instrument [Line Items]                        
Net assets             $ 886,500,000          
Goodwill             401,800,000          
Intangible assets             $ 395,400,000          
OPKO Health Europe                        
Debt Instrument [Line Items]                        
Weighted average interest rate             3.20%       2.10%  
Minimum | OPKO Health Europe                        
Debt Instrument [Line Items]                        
Variable interest rates             1.30%          
Maximum | OPKO Health Europe                        
Debt Instrument [Line Items]                        
Variable interest rates             5.50%          
Convertible Debt                        
Debt Instrument [Line Items]                        
Interest rate on notes payable     4.50%                  
Convertible Debt | Convertible Senior Notes Due 2025                        
Debt Instrument [Line Items]                        
Debt face amount     $ 200,000,000.0                  
Conversion rate     0.2367424                  
Conversion price per share (in dollars per share) | $ / shares     $ 4.22                  
Shares issuable under debt agreement (in shares) | shares     30,000,000                  
Shares issued on converted debt (in shares) | shares             29,250,000          
Proceeds one-time nominal fee             $ 300,000          
Equity component of convertible debt     $ 52,600,000                  
Effective interest rate             11.20%          
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one                        
Debt Instrument [Line Items]                        
Convertible debt, threshold percentage of stock price trigger     130.00%                  
Equivalent redemption price     100.00%                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one | Minimum                        
Debt Instrument [Line Items]                        
Number of trading days | d     20                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one | Maximum                        
Debt Instrument [Line Items]                        
Number of consecutive trading days applicable conversion price | d     30                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two                        
Debt Instrument [Line Items]                        
Convertible debt, threshold percentage of stock price trigger     98.00%                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two | Minimum                        
Debt Instrument [Line Items]                        
Number of trading days | d     5                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two | Maximum                        
Debt Instrument [Line Items]                        
Number of consecutive trading days applicable conversion price | d     5                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three                        
Debt Instrument [Line Items]                        
Convertible debt, threshold percentage of stock price trigger     130.00%                  
Equivalent redemption price     100.00%                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three | Minimum                        
Debt Instrument [Line Items]                        
Number of trading days | d     20                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three | Maximum                        
Debt Instrument [Line Items]                        
Number of consecutive trading days applicable conversion price | d     30                  
Convertible Debt | 5% Convertible Notes                        
Debt Instrument [Line Items]                        
Debt face amount       $ 55,000,000.0                
Interest rate on notes payable       5.00%                
Conversion price per share (in dollars per share) | $ / shares       $ 5.00                
Maturity duration       5 years                
Par value per converted share (in dollars per share) | $ / shares       $ 0.01                
Minimum conversion notice       30 days                
Maximum conversion notice       60 days                
Convertible Debt | Notes Due February 1, 2033                        
Debt Instrument [Line Items]                        
Converted debt amount                 $ 143,200,000      
Senior Notes                        
Debt Instrument [Line Items]                        
Remaining principal             $ 142,674,000       $ 0  
Senior Notes | Notes Due February 1, 2033                        
Debt Instrument [Line Items]                        
Debt face amount   $ 175,000,000.0                    
Interest rate on notes payable   3.00%                    
Equivalent redemption price   100.00%                    
Notes | Notes Due February 1, 2033                        
Debt Instrument [Line Items]                        
Equivalent redemption price           100.00%            
Debt repurchase amount                   $ 28,800,000    
Remaining principal                   $ 3,000,000.0    
Line of Credit                        
Debt Instrument [Line Items]                        
Weighted average interest rate             4.30%       4.70%  
Line of Credit | Unsecured Debt                        
Debt Instrument [Line Items]                        
Interest rate on notes payable                       10.00%
Credit line capacity                       $ 60,000,000
Revolving Credit Facility | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Credit line capacity         $ 175,000,000.0              
Remaining principal             $ 105,300,000          
Higher borrowing capacity option         $ 275,000,000.0              
Remaining borrowing capacity             $ 0.0          
Commitment fee percentage         0.50%              
Swingline | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Credit line capacity         $ 20,000,000.0              
Letter of Credit | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Credit line capacity         $ 20,000,000.0              
LIBOR | Revolving Credit Facility | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Basis spread on variable rate         2.50%              
LIBOR, First 12 Months | Revolving Credit Facility | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Basis spread on variable rate         0.35%              
LIBOR Thereafter | Revolving Credit Facility | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Basis spread on variable rate         0.50%              
LIBOR, First 12 Months, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Basis spread on variable rate         1.35%              
LIBOR, Thereafter, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                        
Debt Instrument [Line Items]                        
Basis spread on variable rate         1.50%              
Common Stock | Convertible Debt | Notes Due February 1, 2033                        
Debt Instrument [Line Items]                        
Shares issued on converted debt (in shares) | shares                 21,539,873      
Dr Frost | Line of Credit | Unsecured Debt                        
Debt Instrument [Line Items]                        
Repayments of lines of credit $ 28,800,000                      
Credit line capacity                       $ 60,000,000