Quarterly report pursuant to Section 13 or 15(d)

Related Party Transactions (Details)

v3.3.0.814
Related Party Transactions (Details)
$ / shares in Units, ft² in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jan. 16, 2014
USD ($)
$ / shares
shares
Oct. 31, 2015
USD ($)
$ / shares
shares
Jul. 31, 2015
USD ($)
shares
May. 31, 2015
USD ($)
Feb. 28, 2014
USD ($)
Sep. 30, 2015
USD ($)
$ / shares
Sep. 30, 2014
USD ($)
Sep. 30, 2015
USD ($)
$ / shares
Sep. 30, 2014
USD ($)
Dec. 31, 2012
USD ($)
Aug. 20, 2015
$ / shares
May. 28, 2015
USD ($)
ft²
May. 05, 2015
$ / shares
Dec. 31, 2014
shares
Aug. 31, 2013
Jan. 31, 2013
USD ($)
Notes | Notes Due February 1, 2033                                
Related Party Transaction [Line Items]                                
Stock price | $ / shares           $ 8.41   $ 8.41                
Debt face amount                               $ 175,000,000.0
MabVax                                
Related Party Transaction [Line Items]                                
Warrants to purchase common shares | shares                           1,700,000    
Ownership percentage           0.00%   0.00%                
ARNO                                
Related Party Transaction [Line Items]                                
Warrants to purchase common shares | shares                           800,000    
Ownership percentage           4.00%   4.00%                
Zebra                                
Related Party Transaction [Line Items]                                
Ownership percentage           28.00%   28.00%                
Sevion                                
Related Party Transaction [Line Items]                                
Invested in common shares     $ 500,000                          
Warrants to purchase common shares | shares     333,333                     500,000    
Ownership percentage           3.00%   3.00%                
Chromadex Corporation                                
Related Party Transaction [Line Items]                                
Ownership percentage           2.00%   2.00%                
Biozone Pharmaceuticals Inc                                
Related Party Transaction [Line Items]                                
Invested in common shares                   $ 1,700,000            
Cocrystal                                
Related Party Transaction [Line Items]                                
Warrants to purchase common shares | shares                           1,000,000    
Ownership percentage           8.00%   8.00%                
Neovasc                                
Related Party Transaction [Line Items]                                
Warrants to purchase common shares | shares                           1,000,000    
Ownership percentage           5.00%   5.00%                
Dr Frost | OPKO Biologics                                
Related Party Transaction [Line Items]                                
Beneficially owned held by members                             5.00%  
Dr. Hsiao and Mr. Rubin | OPKO Biologics                                
Related Party Transaction [Line Items]                                
Beneficially owned held by members                             5.00%  
Frost Gamma Investments Trust and Hsu Gamma Investment, L.P. | Notes | Notes Due February 1, 2033                                
Related Party Transaction [Line Items]                                
Debt face amount                               $ 175,000,000
Teva | FineTech                                
Related Party Transaction [Line Items]                                
Sale of API to TEVA               $ 0 $ 300,000              
Frost Real Estate Holdings LLC                                
Related Party Transaction [Line Items]                                
Area of real estate property (in square feet) | ft²                       25        
Payments per month in first year                       $ 66,000        
Payments per month in fifth year                       75,000        
Rent reduction                       $ 216,000        
FTC Filings | Dr Frost                                
Related Party Transaction [Line Items]                                
Payments for filing fees         $ 280,000                      
Equity Method Investee | Sevion                                
Related Party Transaction [Line Items]                                
Private placement financing       $ 500,000                        
Equity Method Investee | Biozone                                
Related Party Transaction [Line Items]                                
Investment owned, shares | shares 1,000,000                              
Warrants to purchase common shares | shares 1,000,000                              
Additional investment in common shares $ 500,000                              
Private placement financing $ 2,750,000                              
Warrants duration 10 years                              
Warrants exercisable price (in USD per share) | $ / shares $ 0.50                              
Reimbursement Of Travel Expense | Dr Frost                                
Related Party Transaction [Line Items]                                
Reimbursement paid to related party for travel           $ 66,000 $ 110,000 $ 359,000 $ 118,000              
Series C Preferred Stock | Sevion                                
Related Party Transaction [Line Items]                                
Investment owned, shares | shares     66,667                          
Common Stock                                
Related Party Transaction [Line Items]                                
Stock price | $ / shares                     $ 12.38   $ 13.88      
Common Stock | Sevion                                
Related Party Transaction [Line Items]                                
Investment owned, shares | shares     666,667                          
Subsequent Event | MabVax                                
Related Party Transaction [Line Items]                                
Invested in common shares   $ 375,000                            
Investment owned, shares | shares   340,909                            
Stock price | $ / shares   $ 1.10                            
Warrants to purchase common shares | shares   170,454