Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies (Details)

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Commitments and Contingencies (Details) - USD ($)
1 Months Ended 12 Months Ended
Aug. 31, 2017
Dec. 31, 2017
Dec. 31, 2016
Business Acquisition, Contingent Consideration [Line Items]      
Contingent consideration   $ 41,400,000 $ 45,100,000
Issuance of common stock (in shares)     2,611,648
Contingent membership interest 15.00%    
Credit line capacity   197,320,000  
Fixed purchase provisions   82,200,000  
Accrued Expenses      
Business Acquisition, Contingent Consideration [Line Items]      
Contingent consideration   11,800,000 $ 300,000
Other Long-term Liabilities      
Business Acquisition, Contingent Consideration [Line Items]      
Contingent consideration   29,600,000 44,800,000
OPKO Renal      
Business Acquisition, Contingent Consideration [Line Items]      
Payments on loss contingency     25,000,000
BioReference      
Business Acquisition, Contingent Consideration [Line Items]      
Severance Costs   $ 5,800,000 $ 17,900,000
Line of Credit | Veterans Accountable Care Group LLC      
Business Acquisition, Contingent Consideration [Line Items]      
Credit line capacity $ 50,000,000.0    
Line of credit facility, expiration period 5 years    
Interest rate of notes payable 6.50%