Annual report pursuant to Section 13 and 15(d)

Acquisitions, Investments, and Licenses - Summary of Investments (Details)

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Acquisitions, Investments, and Licenses - Summary of Investments (Details) (USD $)
In Thousands, except Per Share data, unless otherwise specified
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Investment [Line Items]      
Investment, available for sale $ 4,301 $ 5,335  
Plus unrealized/realized gains on investments, options and warrants, net 12,766    
Less accumulated losses in investees (18,474)    
Investments, net 30,653 [1] 15,636 [1]  
Share price (in dollars per share)     $ 3.27
Cocrystal [Member]
     
Investment [Line Items]      
Ownership percentage 16.00%    
Investment, equity method 2,500    
Underlying equity in net assets 205    
Neovasc [Member]
     
Investment [Line Items]      
Ownership percentage 6.00%    
Investment, equity method 3,798    
Underlying equity in net assets 325    
Fabrus [Member]
     
Investment [Line Items]      
Ownership percentage 12.00%    
Investment, equity method 750    
Underlying equity in net assets (160)    
BZNE [Member]
     
Investment [Line Items]      
Ownership percentage 16.00%    
Investment, equity method 2,976    
Underlying equity in net assets (1,686)    
RXi [Member]
     
Investment [Line Items]      
Ownership percentage 19.00%    
Investment, equity method 15,000    
Underlying equity in net assets 2,444    
Pharmasynthez [Member]
     
Investment [Line Items]      
Ownership percentage 11.00%    
Investment, equity method 5,036    
Underlying equity in net assets 5,156    
Zebra [Member]
     
Investment [Line Items]      
Ownership percentage 19.00%    
Investment, equity method 2,000    
Underlying equity in net assets 1,220    
TESARO [Member]
     
Investment [Line Items]      
Ownership percentage 1.00%    
Investment, available for sale 56    
Share price (in dollars per share) $ 28.24    
Neovasc Options [Member]
     
Investment [Line Items]      
Investment, available for sale 925    
Share price (in dollars per share) $ 4.10    
ChromaDex [Member]
     
Investment [Line Items]      
Ownership percentage 1.00%    
Investment, available for sale 1,320    
Share price (in dollars per share) $ 1.52    
ARNO [Member]
     
Investment [Line Items]      
Ownership percentage 5.00%    
Investment, available for sale $ 2,000    
Share price (in dollars per share) $ 3.20    
[1] As of December 31, 2013 and 2012, total assets include $6.7 million and $5.6 million, respectively, and total liabilities include $10.4 million and $5.5 million, respectively related to SciVac Ltd (“SciVac”), previously known as SciGen (I.L.) Ltd, a consolidated variable interest entity. SciVac’s consolidated assets are owned by SciVac and the holders of SciVac’s consolidated liabilities have no recourse against us. Refer to Note 3.