Annual report pursuant to Section 13 and 15(d)

Condensed Consolidated Statement of Equity

v2.4.1.9
Condensed Consolidated Statement of Equity (USD $)
In Thousands, except Share data, unless otherwise specified
Total
OPKO Uruguay Ltda.
Inspiro
OPKO Health Europe
OPKO Brazil
OPKO Renal
OPKO Biologics
OPKO Lab
Common Stock
Common Stock
OPKO Health Europe
Common Stock
OPKO Brazil
Common Stock
OPKO Renal
Common Stock
OPKO Biologics
Common Stock
OPKO Lab
Treasury
Treasury
OPKO Uruguay Ltda.
Treasury
Inspiro
Treasury
OPKO Health Europe
Additional Paid-In Capital
Additional Paid-In Capital
OPKO Uruguay Ltda.
Additional Paid-In Capital
Inspiro
Additional Paid-In Capital
OPKO Health Europe
Additional Paid-In Capital
OPKO Brazil
Additional Paid-In Capital
OPKO Renal
Additional Paid-In Capital
OPKO Biologics
Additional Paid-In Capital
OPKO Lab
Accumulated Other Comprehensive Income
Accumulated Deficit
Noncontrolling Interests
Series D Preferred Stock
Series D Preferred Stock
Common Stock
Series D Preferred Stock
Additional Paid-In Capital
Notes
Notes
Common Stock
Notes
Additional Paid-In Capital
Beginning balance at Dec. 31, 2011 $ 160,882us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest               $ 2,975us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          $ (8,092)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
      $ 524,814us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
              $ 907us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
$ (359,722)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
$ 0us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Beginning balance, shares at Dec. 31, 2011                 297,503,033us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          (2,488,477)us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                       
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                                                      
Equity-based compensation expense 5,131us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue                                   5,131us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock options 2,234us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised               10us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  2,224us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock options, shares                 1,019,967us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Exercise of Common Stock warrants 45opk_StockIssuedDuringPeriodValueWarrantsExercised               1opk_StockIssuedDuringPeriodValueWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  44opk_StockIssuedDuringPeriodValueWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock warrants, shares                 65,015opk_StockIssuedDuringPeriodSharesWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Adjustment of Common Stock Value 0opk_AdjustmentOfCommonStockValue               (1)opk_AdjustmentOfCommonStockValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  1opk_AdjustmentOfCommonStockValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Adjustment of Common Stock Shares                 (100,000)opk_AdjustmentOfCommonStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Issuance of Common Stock in connection with acquisition       805us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
      32,888us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOLabMember
          71us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOLabMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
      635us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
      170us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
      32,817us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOLabMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                 
Issuance of Common Stock in connection with acquisition, shares                           7,072,748us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOLabMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
      195,421us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                 
Net loss attributable to common shareholders (29,048)us-gaap_NetIncomeLoss                                                     (29,048)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
             
Net loss attributable to noncontrolling interests (492)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest                                                       (492)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Other comprehensive loss 6,449us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent                                                   6,449us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
               
Ending balance at Dec. 31, 2012 178,894us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest               3,056us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          (7,457)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
      565,201us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
              7,356us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
(388,770)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
(492)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Ending balance, shares at Dec. 31, 2012                 305,560,763us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          (2,293,056)us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                       
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                                                      
Equity-based compensation expense 10,983us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue                                   10,983us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock options 22,796us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised               92us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  22,704us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock options, shares                 9,244,971us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Exercise of Common Stock warrants 628opk_StockIssuedDuringPeriodValueWarrantsExercised               15opk_StockIssuedDuringPeriodValueWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  613opk_StockIssuedDuringPeriodValueWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock warrants, shares                 1,487,774opk_StockIssuedDuringPeriodSharesWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Preferred Stock dividend                                                           (3,015)us-gaap_DividendsPreferredStockCash
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_SeriesDPreferredStockMember
  (3,015)us-gaap_DividendsPreferredStockCash
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_SeriesDPreferredStockMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
     
Conversion of Preferred Stock                                                           24,386us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_SeriesDPreferredStockMember
113us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_SeriesDPreferredStockMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
24,273us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_SeriesDPreferredStockMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
20,839us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_ConvertibleNotesPayableMember
24us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_ConvertibleNotesPayableMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
20,815us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_ConvertibleNotesPayableMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
Conversion of Preferred Stock, shares                                                             11,290,320us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_SeriesDPreferredStockMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
    2,396,145us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_ConversionOfStockByUniqueDescriptionAxis
= us-gaap_ConvertibleNotesPayableMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
 
Issuance of Common Stock in connection with acquisition         435us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBrazilMember
146,902us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
586,643us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBiologicsMember
      1us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBrazilMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
205us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
637us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBiologicsMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  434us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBrazilMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
146,697us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
586,006us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBiologicsMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                   
Issuance of Common Stock in connection with acquisition, shares                     64,684us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBrazilMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
20,517,030us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
63,670,805us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOBiologicsMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                           
Stock Issued During Period, Value, Deferred Payment       4,435opk_StockIssuedDuringPeriodValueDeferredPayment
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
          5opk_StockIssuedDuringPeriodValueDeferredPayment
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                      4,430opk_StockIssuedDuringPeriodValueDeferredPayment
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                         
Stock Issued During Period, Share, Contingent Consideration                                   28,993opk_StockIssuedDuringPeriodShareContingentConsideration
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                 
Stock Issued During Period, Value, Contingent Consideration       337opk_StockIssuedDuringPeriodValueContingentConsideration
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
                          95opk_StockIssuedDuringPeriodValueContingentConsideration
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
      242opk_StockIssuedDuringPeriodValueContingentConsideration
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                         
Stock Issued During Period, Share, Deferred Payment, shares                   585,703opk_StockIssuedDuringPeriodShareDeferredPayment
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOHealthEuropeMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                 
Net loss attributable to common shareholders (114,407)us-gaap_NetIncomeLoss                                                     (114,407)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
             
Net loss attributable to noncontrolling interests (2,939)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest                                                       (2,939)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Other comprehensive loss (3,938)us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent                                                   (3,938)us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
               
Ending balance at Dec. 31, 2013 872,979us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest [1]               4,148us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          (7,362)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
      1,379,383us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
              3,418us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
(503,177)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
(3,431)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Ending balance, shares at Dec. 31, 2013                 414,818,195us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          (2,264,063)us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                       
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                                                      
Equity-based compensation expense 14,737us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue                                   14,737us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock options 5,915us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised               23us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  5,892us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock options, shares 2,723,666us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised               2,328,947us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Exercise of Common Stock warrants 7,013opk_StockIssuedDuringPeriodValueWarrantsExercised               31opk_StockIssuedDuringPeriodValueWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                  6,982opk_StockIssuedDuringPeriodValueWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                               
Exercise of Common Stock warrants, shares                 3,063,894opk_StockIssuedDuringPeriodSharesWarrantsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
                                                   
Issuance of Common Stock in connection with acquisition 95,665us-gaap_StockIssuedDuringPeriodValueAcquisitions 159us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOUruguayLtda.Member
8,566us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_InspiroMedicalLtd.Member
          110us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
    22us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
      61us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOUruguayLtda.Member
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
3,250us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_InspiroMedicalLtd.Member
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
  95,555us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
98us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOUruguayLtda.Member
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
5,316us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_InspiroMedicalLtd.Member
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                           
Issuance of Common Stock in connection with acquisition, shares                 10,974,431us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
    2,236,210us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
      19,140us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKOUruguayLtda.Member
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
999,556us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_BusinessAcquisitionAxis
= opk_InspiroMedicalLtd.Member
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                   
Stock Issued During Period, Value, Contingent Consideration           21,155opk_StockIssuedDuringPeriodValueContingentConsideration
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
                                  21,133opk_StockIssuedDuringPeriodValueContingentConsideration
/ us-gaap_BusinessAcquisitionAxis
= opk_OPKORenalMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
                     
Net loss attributable to common shareholders (171,666)us-gaap_NetIncomeLoss                                                     (171,666)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
             
Net loss attributable to noncontrolling interests (2,972)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest                                                       (2,972)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Other comprehensive loss (15,810)us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent                                                   (15,810)us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
               
Ending balance at Dec. 31, 2014 $ 835,741us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest [1]               $ 4,334us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          $ (4,051)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
      $ 1,529,096us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
              $ (12,392)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedOtherComprehensiveIncomeMember
$ (674,843)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
$ (6,403)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_NoncontrollingInterestMember
           
Ending balance, shares at Dec. 31, 2014                 433,421,677us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
          (1,245,367)us-gaap_SharesOutstanding
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_TreasuryStockMember
                                       
[1] As of December 31, 2014 and December 31, 2013, total assets include $7.6 million and $6.7 million, respectively, and total liabilities include $12.1 million and $10.4 million, respectively, related to SciVac, previously known as SciGen (I.L.) Ltd, a consolidated variable interest entity. SciVac’s consolidated assets are owned by SciVac and SciVac’s consolidated liabilities have no recourse against us. Refer to Note 4.