Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies (Details)

v2.4.1.9
Summary of Significant Accounting Policies (Details) (USD $)
12 Months Ended 9 Months Ended 1 Months Ended 3 Months Ended
Dec. 31, 2014
Segment
Dec. 31, 2013
Dec. 31, 2012
Sep. 30, 2013
Jun. 30, 2014
Dec. 31, 2014
Jan. 31, 2013
Jan. 30, 2013
Apr. 30, 2013
Summary of Significant Accounting Policies [Line Items]                  
Net Cash Provided by (Used in) Financing Activities $ 7,263,000us-gaap_NetCashProvidedByUsedInFinancingActivities $ 183,635,000us-gaap_NetCashProvidedByUsedInFinancingActivities $ 6,031,000us-gaap_NetCashProvidedByUsedInFinancingActivities            
Gains (Losses) on Extinguishment of Debt 2,668,000us-gaap_GainsLossesOnExtinguishmentOfDebt 972,000us-gaap_GainsLossesOnExtinguishmentOfDebt 0us-gaap_GainsLossesOnExtinguishmentOfDebt            
Net Cash Provided by (Used in) Operating Activities (90,379,000)us-gaap_NetCashProvidedByUsedInOperatingActivities (55,653,000)us-gaap_NetCashProvidedByUsedInOperatingActivities (25,415,000)us-gaap_NetCashProvidedByUsedInOperatingActivities            
Maximum Number of Days Interest Bearing Instruments with Original Maturities to Consider as Cash Equivalent 90 days                
Maximum Number of Days Interest Bearing Instruments with Remaining Maturities to Consider as Marketable Securities 90 days                
Short Term Investments Maturities Period Minimum 90 days                
Goodwill and intangible assets 1,100,000,000opk_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets 1,100,000,000opk_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets       1,100,000,000opk_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedGoodwillandIntangibleAssets      
Amortization of intangible assets 10,919,000us-gaap_AmortizationOfIntangibleAssets 11,133,000us-gaap_AmortizationOfIntangibleAssets 8,335,000us-gaap_AmortizationOfIntangibleAssets            
Amortization expense in 2015 10,900,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths         10,900,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths      
Amortization expense in 2016 9,700,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo         9,700,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo      
Amortization expense in 2017 9,000,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree         9,000,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree      
Amortization expense in 2018 6,900,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour         6,900,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour      
Amortization expense in 2019 6,300,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive         6,300,000us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive      
Short Term Investments Maturities Period Maximum 1 year                
Long Term Investments Maturities Period Minimum 1 year                
Depreciation 4,000,000us-gaap_Depreciation 4,100,000us-gaap_Depreciation 1,800,000us-gaap_Depreciation            
Revenue from services 8,666,000us-gaap_SalesRevenueServicesNet 11,658,000us-gaap_SalesRevenueServicesNet 1,749,000us-gaap_SalesRevenueServicesNet            
Revenue From Transfer Of Intellectual Property 5,476,000opk_RevenueFromTransferOfIntellectualProperty 16,711,000opk_RevenueFromTransferOfIntellectualProperty 0opk_RevenueFromTransferOfIntellectualProperty            
Total deferred revenue related to other revenues 6,700,000us-gaap_DeferredRevenue 8,300,000us-gaap_DeferredRevenue       6,700,000us-gaap_DeferredRevenue      
Allowance for doubtful accounts receivable (1,906,000)us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent (1,884,000)us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent       (1,906,000)us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent      
Equity-based compensation expense for continuing operations 14,779,000us-gaap_ShareBasedCompensation 10,983,000us-gaap_ShareBasedCompensation 5,131,000us-gaap_ShareBasedCompensation            
Number of reportable segments 2us-gaap_NumberOfReportableSegments                
RXi common stock received 0opk_RevenueFromSaleOfIntellectualProperty 12,500,000opk_RevenueFromSaleOfIntellectualProperty 0opk_RevenueFromSaleOfIntellectualProperty            
Pharmaceutical                  
Summary of Significant Accounting Policies [Line Items]                  
Number of operating segments 2us-gaap_NumberOfOperatingSegments
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= opk_PharmaceuticalMember
               
Diagnostics                  
Summary of Significant Accounting Policies [Line Items]                  
Number of operating segments 2us-gaap_NumberOfOperatingSegments
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Neovasc                  
Summary of Significant Accounting Policies [Line Items]                  
Revenue from services 800,000us-gaap_SalesRevenueServicesNet
/ dei_LegalEntityAxis
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  1,400,000us-gaap_SalesRevenueServicesNet
/ dei_LegalEntityAxis
= opk_NeovascMember
800,000us-gaap_SalesRevenueServicesNet
/ dei_LegalEntityAxis
= opk_NeovascMember
         
Minimum                  
Summary of Significant Accounting Policies [Line Items]                  
Intangible assets, estimated useful lives 3 years                
Property, Plant and Equipment, Useful Life 5 years                
Maximum                  
Summary of Significant Accounting Policies [Line Items]                  
Intangible assets, estimated useful lives 10 years                
Property, Plant and Equipment, Useful Life 10 years                
Restatement Adjustment                  
Summary of Significant Accounting Policies [Line Items]                  
Net Cash Provided by (Used in) Financing Activities 6,400,000us-gaap_NetCashProvidedByUsedInFinancingActivities
/ us-gaap_StatementScenarioAxis
= us-gaap_RestatementAdjustmentMember
2,500,000us-gaap_NetCashProvidedByUsedInFinancingActivities
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Net Cash Provided by (Used in) Operating Activities (6,400,000)us-gaap_NetCashProvidedByUsedInOperatingActivities
/ us-gaap_StatementScenarioAxis
= us-gaap_RestatementAdjustmentMember
(2,500,000)us-gaap_NetCashProvidedByUsedInOperatingActivities
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Notes | Notes Due February 1, 2033                  
Summary of Significant Accounting Policies [Line Items]                  
Gains (Losses) on Extinguishment of Debt         2,700,000us-gaap_GainsLossesOnExtinguishmentOfDebt
/ us-gaap_DebtInstrumentAxis
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/ us-gaap_LongtermDebtTypeAxis
= us-gaap_ConvertibleNotesPayableMember
       
Interest rate of notes payable 3.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
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3.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
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= opk_NotesDueFebruary12033Member
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= us-gaap_ConvertibleNotesPayableMember
      3.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
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= us-gaap_ConvertibleNotesPayableMember
3.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
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3.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
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= us-gaap_ConvertibleNotesPayableMember
 
Notes | Notes Due February 1, 2033 | Other Expense                  
Summary of Significant Accounting Policies [Line Items]                  
Gains (Losses) on Extinguishment of Debt   (8,700,000)us-gaap_GainsLossesOnExtinguishmentOfDebt
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Notes | Notes Due February 1, 2033 | Other Expense | Restatement Adjustment                  
Summary of Significant Accounting Policies [Line Items]                  
Gains (Losses) on Extinguishment of Debt 9,700,000us-gaap_GainsLossesOnExtinguishmentOfDebt
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= us-gaap_OtherExpenseMember
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_ConvertibleNotesPayableMember
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= us-gaap_RestatementAdjustmentMember
9,700,000us-gaap_GainsLossesOnExtinguishmentOfDebt
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= us-gaap_OtherExpenseMember
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_ConvertibleNotesPayableMember
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= us-gaap_RestatementAdjustmentMember
             
Notes | Notes Due February 1, 2033 | Deferred Derivative Gain (Loss)                  
Summary of Significant Accounting Policies [Line Items]                  
Embedded Derivative, Loss on Embedded Derivative   43,100,000us-gaap_EmbeddedDerivativeLossOnEmbeddedDerivative
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= us-gaap_DeferredDerivativeGainLossMember
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= us-gaap_ConvertibleNotesPayableMember
             
Notes | Notes Due February 1, 2033 | Deferred Derivative Gain (Loss) | Restatement Adjustment                  
Summary of Significant Accounting Policies [Line Items]                  
Embedded Derivative, Loss on Embedded Derivative 9,700,000us-gaap_EmbeddedDerivativeLossOnEmbeddedDerivative
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Computer Software, Intangible Asset                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 3 years                
Machinery and Equipment | Minimum                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 5 years                
Machinery and Equipment | Maximum                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 8 years                
Furniture and Fixtures | Minimum                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 5 years                
Furniture and Fixtures | Maximum                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 10 years                
Land, Buildings and Improvements | Minimum                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 10 years                
Land, Buildings and Improvements | Maximum                  
Summary of Significant Accounting Policies [Line Items]                  
Property, Plant and Equipment, Useful Life 40 years                
RXi Pharmaceuticals Corporation                  
Summary of Significant Accounting Policies [Line Items]                  
RXi common stock received   12,500,000opk_RevenueFromSaleOfIntellectualProperty
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Pharmsynthez                  
Summary of Significant Accounting Policies [Line Items]                  
License and Services Revenue 500,000us-gaap_LicenseAndServicesRevenue
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3,800,000us-gaap_LicenseAndServicesRevenue
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Total deferred revenue related to other revenues                 9,500,000us-gaap_DeferredRevenue
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TESARO | Collaborative Arrangement                  
Summary of Significant Accounting Policies [Line Items]                  
Collaborative Arrangement, Milestone Payment Received           $ 5,000,000opk_CollaborativeArrangementMilestonePaymentReceived
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