Annual report pursuant to Section 13 and 15(d)

Loss Per Share (Details)

v2.4.1.9
Loss Per Share (Details)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Number of common stock warrant and common stock options exercised 5,787,983opk_StockIssuedDuringPeriodSharesStockOptionsandWarrantsExercised 10,881,570opk_StockIssuedDuringPeriodSharesStockOptionsandWarrantsExercised 1,086,361opk_StockIssuedDuringPeriodSharesStockOptionsandWarrantsExercised
Number of common stock issued for stock warrant and stock options exercised 5,392,741opk_StockIssuedDuringPeriodSharesStockOptionsandWarrantsExercisedNetofSharesSurrenderedinLieuofCashPayment 10,732,745opk_StockIssuedDuringPeriodSharesStockOptionsandWarrantsExercisedNetofSharesSurrenderedinLieuofCashPayment 1,084,982opk_StockIssuedDuringPeriodSharesStockOptionsandWarrantsExercisedNetofSharesSurrenderedinLieuofCashPayment
Shares surrendered in lieu of cash payment 426opk_SharesSurrenderedInLieuOfCashPayment 148,825opk_SharesSurrenderedInLieuOfCashPayment 1,379opk_SharesSurrenderedInLieuOfCashPayment
Common stock investments, available for sale      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potential common shares 28,456,149us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_CommonStockMember
32,105,859us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_CommonStockMember
26,695,436us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_CommonStockMember