Annual report pursuant to Section 13 and 15(d)

Composition of Certain Financial Statement Captions - Fair Value Assigned to Intangible Asset Classes (Details)

v3.6.0.2
Composition of Certain Financial Statement Captions - Fair Value Assigned to Intangible Asset Classes (Details) - USD ($)
1 Months Ended 12 Months Ended
Aug. 31, 2015
May 31, 2015
Dec. 31, 2016
Aug. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Aug. 31, 2013
Dec. 31, 2012
Aug. 31, 2012
Dec. 31, 2011
Feb. 28, 2011
Feb. 28, 2010
Oct. 31, 2009
Fair values assigned to major intangible asset classes upon each acquisition                          
Goodwill     $ 704,603,000   $ 743,348,000 $ 224,292,000              
In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               $ 0         $ 0
Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       $ 0       0         0
Weighted average amortization period     9 years                    
Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
Weighted average amortization period     5 years                    
Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 $ 0       0
Bio-Reference                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets $ 545,250,000   $ 488,700,000                    
Goodwill $ 401,821,000   $ 401,821,000                    
Weighted average amortization period 13 years                        
Bio-Reference | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets $ 100,600,000                        
Bio-Reference | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets 0                        
Bio-Reference | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets 389,800,000                        
Bio-Reference | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets 0                        
Bio-Reference | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets 7,750,000                        
Bio-Reference | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets 47,100,000                        
Weighted average amortization period     5 years                    
Bio-Reference | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets $ 0                        
CURNA                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     $ 10,290,000    
Goodwill                     4,827,000    
CURNA | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     0    
CURNA | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     10,000,000    
CURNA | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     0    
CURNA | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     0    
CURNA | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     0    
CURNA | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     0    
CURNA | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                     $ 290,000    
EirGen                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   $ 38,634,000                      
Goodwill   $ 83,373,000                      
Weighted average amortization period   15 years                      
EirGen | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   $ 0                      
EirGen | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   560,000                      
EirGen | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   $ 34,155,000                      
Weighted average amortization period   15 years 9 months 18 days                      
EirGen | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   $ 0                      
EirGen | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   0                      
EirGen | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   0                      
EirGen | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets   $ 3,919,000                      
FineTech                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   $ 18,800,000      
Goodwill                   11,623,000      
FineTech | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   2,700,000      
FineTech | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   0      
FineTech | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   14,200,000      
FineTech | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   0      
FineTech | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   1,500,000      
FineTech | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   400,000      
FineTech | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                   $ 0      
OPKO Biologics                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             $ 590,200,000            
Goodwill             139,784,000            
OPKO Biologics | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             0            
OPKO Biologics | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             590,200,000            
OPKO Biologics | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             0            
OPKO Biologics | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             0            
OPKO Biologics | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             0            
OPKO Biologics | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             0            
OPKO Biologics | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets             $ 0            
OPKO Chile                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         10,806,000
Goodwill                         5,441,000
OPKO Chile | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
OPKO Chile | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
OPKO Chile | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         3,945,000
OPKO Chile | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         5,829,000
OPKO Chile | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
OPKO Chile | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         1,032,000
OPKO Chile | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         0
OPKO Diagnostics                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         44,400,000
Goodwill                         17,977,000
OPKO Diagnostics | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                         $ 44,400,000
OPKO Health Europe                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 8,378,000        
Goodwill                 8,062,000        
OPKO Health Europe | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 3,017,000        
OPKO Health Europe | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 1,459,000        
OPKO Health Europe | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 436,000        
OPKO Health Europe | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 2,930,000        
OPKO Health Europe | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 187,000        
OPKO Health Europe | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                 $ 349,000        
OPKO Lab                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               14,030,000          
Goodwill               29,629,000          
OPKO Lab | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               1,370,000          
OPKO Lab | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               3,860,000          
OPKO Lab | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               6,900,000          
OPKO Lab | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               1,830,000          
OPKO Lab | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets               $ 70,000          
OPKO Renal                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       $ 191,740,000  
Goodwill                       2,411,000  
OPKO Renal | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       0  
OPKO Renal | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       191,530,000  
OPKO Renal | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       0  
OPKO Renal | Product registrations                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       0  
OPKO Renal | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       0  
OPKO Renal | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       0  
OPKO Renal | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets                       $ 210,000  
Transition Therapeutics, Inc.                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       41,000,000                  
Goodwill       3,453,000                  
Transition Therapeutics, Inc. | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       0                  
Transition Therapeutics, Inc. | In-process research and development                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       41,000,000                  
Transition Therapeutics, Inc. | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       0                  
Transition Therapeutics, Inc. | Covenants not to compete                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       0                  
Transition Therapeutics, Inc. | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       0                  
Transition Therapeutics, Inc. | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Total identified intangible assets       $ 0                  
Minimum | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     8 years                    
Minimum | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     6 years                    
Minimum | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     4 years                    
Minimum | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     3 years                    
Maximum | Technologies                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     12 years                    
Maximum | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     20 years                    
Maximum | Trade names                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     5 years                    
Maximum | Other                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     10 years                    
Maximum | Bio-Reference | Customer relationships                          
Fair values assigned to major intangible asset classes upon each acquisition                          
Weighted average amortization period     19 years 3 months 18 days