Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies (Details)

v3.6.0.2
Commitments and Contingencies (Details) - USD ($)
$ in Millions
9 Months Ended 12 Months Ended
Sep. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Business Acquisition, Contingent Consideration [Line Items]      
Contingent consideration   $ 45.1 $ 54.4
Issuance of common stock (in shares)   2,611,648 1,194,337
Fixed purchase provisions   $ 90.3  
Accrued Expenses      
Business Acquisition, Contingent Consideration [Line Items]      
Contingent consideration   0.3 $ 22.2
Other Long-term Liabilities      
Business Acquisition, Contingent Consideration [Line Items]      
Contingent consideration   44.8 32.3
OPKO Renal      
Business Acquisition, Contingent Consideration [Line Items]      
Payments on loss contingency   $ 25.0 $ 20.0
Bio-Reference      
Business Acquisition, Contingent Consideration [Line Items]      
Severance Costs $ 17.9    
Bio-Reference      
Business Acquisition, Contingent Consideration [Line Items]      
Period in Preferred Provider Organization 20 years