Quarterly report pursuant to Section 13 or 15(d)

Acquisitions, Investments and Licenses - Bio-Reference Purchase Price Allocation (Details)

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Acquisitions, Investments and Licenses - Bio-Reference Purchase Price Allocation (Details) - USD ($)
$ in Thousands
Aug. 20, 2015
Mar. 31, 2016
Dec. 31, 2015
Aug. 31, 2015
Business Acquisition [Line Items]        
Goodwill   $ 746,961 $ 743,348  
Bio Reference        
Business Acquisition [Line Items]        
Value of OPKO Common Stock issued to Bio-Reference shareholders $ 947,889      
Value of replacement stock options awards to holders of Bio-Reference stock options 2,259     $ 2,259
Cash paid at closing date 950,148      
Cash and cash equivalents 15,800      
Accounts receivable 168,164      
Inventory 19,674      
Other current assets, principally deferred tax assets 61,135      
Total current assets 264,773      
Property, plant and equipment 112,457      
Intangible assets 542,900      
Goodwill 440,837 $ 440,800    
Investments 5,326      
Other assets 13,265      
Total assets 1,379,558      
Accounts payable and accrued expenses (108,216)      
Income taxes payable (437)      
Lines of credit and notes payable (65,701)      
Capital lease obligations (18,293)      
Deferred tax liability (non-current) (236,763)      
Total purchase price 950,148      
Trade names | Bio Reference        
Business Acquisition [Line Items]        
Intangible assets 47,100      
Customer relationships | Bio Reference        
Business Acquisition [Line Items]        
Intangible assets 395,200      
Technology | Bio Reference        
Business Acquisition [Line Items]        
Intangible assets $ 100,600