Quarterly report pursuant to Section 13 or 15(d)

Subsequent Events (Details)

v3.4.0.3
Subsequent Events (Details)
$ / shares in Units, $ in Millions
1 Months Ended 3 Months Ended
Apr. 06, 2016
d
conversion_right
$ / shares
Apr. 01, 2015
d
$ / shares
Aug. 30, 2013
conversion_right
Jan. 30, 2013
$ / shares
May. 09, 2016
USD ($)
Mar. 31, 2016
$ / shares
Convertible Notes | Notes Due February 1, 2033            
Debt Instrument [Line Items]            
Common stock trigger price   $ 9.19        
Convertible debt, threshold percentage of stock price trigger   130.00%   130.00%    
Conversion price per share   $ 7.07   $ 7.07   $ 7.07
Number of trading days | d   20        
Number of consecutive trading days applicable conversion price   30 days        
Conversion right triggered | conversion_right     1      
Conversion rate           0.1414827
Subsequent Event | Convertible Notes | Notes Due February 1, 2033            
Debt Instrument [Line Items]            
Common stock trigger price $ 9.19          
Convertible debt, threshold percentage of stock price trigger 130.00%          
Conversion price per share $ 7.07          
Number of trading days | d 20          
Number of consecutive trading days applicable conversion price 30 days          
Conversion right triggered | conversion_right 1          
Conversion rate 0.1414827          
Development and License Agreement | Scenario, Forecast | Subsequent Event            
Debt Instrument [Line Items]            
License revenue, initial payment | $         $ 50  
License fees, collection period after effective date of agreement         10 days  
Aggregate milestone revenue, maximum | $         $ 232  
Royalty revenue, obligation period after first product sale         10 years  
Exclusive Option | Subsequent Event            
Debt Instrument [Line Items]            
Aggregate milestone revenue, maximum | $         $ 555