OPKO Health was formed in 2007 when the ophthalmic pharmaceutical companies Acuity Pharmaceuticals and the Froptix Corporation merge with eXegenics Inc.

OPKO Health common stock is traded on the NASDAQ under the symbol OPK.

The company's most recent investor presentation is available in the "Investors" section on the company's website. It can also be accessed at the "Events" page of the "Investors" section on the company's website.

The fiscal year ends on December 31.

No.

OPKO Health does not offer a direct stock purchase plan. Shares of the company can be purchased through a brokerage company.

OPKO Health, Inc. has not declared or paid cash dividends. The company has retained earnings for the operation and expansion of its business and does not anticipate paying any cash dividends in the foreseeable future.

The date and location will be published in the company's proxy statement, which can be found on the "SEC Filings" section in the "Investors" section on the company's website.

OPKO Health Corporate Headquarters
4400 Biscayne Blvd.
Miami, FL 33137
Tel: (305) 575-4100

American Stock Transfer & Trust Company, LLC
6201 15th Ave.
Brooklyn, NY 11209
Toll-free at (877) 248-6417 or
(718) 921-8317
www.amstock.com

To replace lost stock certificates, please contact OPKO Health's transfer agent.

To change your address, please contact OPKO Health's transfer agent.

For questions related to the exchange of BRLI shares for OPK shares, please contact OPKO Health's transfer agent.