Quarterly report pursuant to Section 13 or 15(d)

Related Party Transactions (Details)

v3.5.0.2
Related Party Transactions (Details)
$ / shares in Units, ft² in Thousands, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2016
USD ($)
shares
Aug. 31, 2016
USD ($)
$ / shares
shares
Jan. 31, 2016
USD ($)
shares
Nov. 30, 2015
USD ($)
shares
Oct. 31, 2015
USD ($)
$ / shares
shares
Jul. 31, 2015
USD ($)
shares
Sep. 30, 2016
USD ($)
shares
Sep. 30, 2015
USD ($)
Sep. 30, 2016
USD ($)
shares
Sep. 30, 2015
USD ($)
Aug. 31, 2015
$ / shares
May 31, 2015
$ / shares
May 28, 2015
USD ($)
ft²
Zebra                          
Related Party Transaction [Line Items]                          
Stock ownership percentage                 29.00%        
Equity method investment, ownership percentage 29.00%           29.00%   29.00%        
Equity method investment, additional investment in period | $       $ 1,000                  
Sevion                          
Related Party Transaction [Line Items]                          
Equity method investment, ownership percentage 3.00%           3.00%   3.00%        
Equity method investment, additional investment in period | $           $ 500              
Number of shares into which warrants may be converted (in shares) 500,000           500,000   500,000        
Neovasc                          
Related Party Transaction [Line Items]                          
Equity method investment, ownership percentage 4.00%           4.00%   4.00%        
Number of shares into which warrants may be converted (in shares) 100,000           100,000   100,000        
ChromaDex Corporation                          
Related Party Transaction [Line Items]                          
Available-for-sale investment, ownership percentage 2.00%           2.00%   2.00%        
MabVax                          
Related Party Transaction [Line Items]                          
Available-for-sale investment, ownership percentage 4.00%           4.00%   4.00%        
Number of shares into which warrants may be converted (in shares) 700,000           700,000   700,000        
Available-for-sale investment, additional investment in period | $   $ 1,000     $ 400                
Stock price per share (in dollars per share) | $ / shares         $ 1.10                
COCP                          
Related Party Transaction [Line Items]                          
Equity method investment, ownership percentage 8.00%           8.00%   8.00%        
Number of shares into which warrants may be converted (in shares) 1,000,000           1,000,000   1,000,000        
Available-for-sale investment, additional investment in period | $ $ 2,000                        
ARNO                          
Related Party Transaction [Line Items]                          
Available-for-sale investment, ownership percentage 5.00%           5.00%   5.00%        
Number of shares into which warrants may be converted (in shares) 2,200,000           2,200,000   2,200,000        
Available-for-sale investment, additional investment in period | $   $ 300 $ 300                    
InCellDx, Inc                          
Related Party Transaction [Line Items]                          
Equity method investment, ownership percentage 27.00%           27.00%   27.00%        
Number of shares into which warrants may be converted (in shares) 700,000           700,000   700,000        
Frost Real Estate Holdings LLC                          
Related Party Transaction [Line Items]                          
Area of real estate property (in square feet) | ft²                         25
Lease payments per month in first year | $                         $ 66
Lease payments per month in fifth year | $                         75
Rent reduction | $                         $ 200
Reimbursement Of Travel Expense | Dr Frost                          
Related Party Transaction [Line Items]                          
Reimbursement paid to related party for travel | $             $ 154 $ 66 $ 274 $ 359      
Series C Preferred Stock | Sevion                          
Related Party Transaction [Line Items]                          
Equity method investment, additional investment in period (in shares)           66,667              
Common Stock                          
Related Party Transaction [Line Items]                          
Stock price per share (in dollars per share) | $ / shares   $ 9.10                 $ 12.38 $ 13.88  
Common Stock | Sevion                          
Related Party Transaction [Line Items]                          
Equity method investment, additional investment in period (in shares)           666,667              
Number of shares into which warrants may be converted (in shares)           333,333              
Common Stock | MabVax                          
Related Party Transaction [Line Items]                          
Number of shares into which warrants may be converted (in shares)   415,800     170,454                
Available-for-sale investment, additional investment in period (in shares)   207,900     340,909                
Common Stock | COCP                          
Related Party Transaction [Line Items]                          
Available-for-sale investment, additional investment in period (in shares) 4,878,050                        
Common Stock | ARNO                          
Related Party Transaction [Line Items]                          
Number of shares into which warrants may be converted (in shares)   357,142                      
Available-for-sale investment, additional investment in period (in shares)   714,285 714,285                    
Series A-2 Preferred Stock | Zebra                          
Related Party Transaction [Line Items]                          
Equity method investment, additional investment in period (in shares)       420,000