Quarterly report pursuant to Section 13 or 15(d)

Related Party Transactions (Details)

v3.10.0.1
Related Party Transactions (Details)
1 Months Ended 3 Months Ended 6 Months Ended
May 31, 2018
shares
Apr. 30, 2018
shares
Feb. 28, 2018
USD ($)
Nov. 30, 2017
USD ($)
shares
Jul. 31, 2017
USD ($)
shares
May 31, 2017
USD ($)
shares
Apr. 30, 2017
USD ($)
shares
Nov. 30, 2016
USD ($)
Aug. 31, 2016
USD ($)
shares
Jun. 30, 2018
USD ($)
shares
Jun. 30, 2017
USD ($)
Jun. 30, 2018
USD ($)
shares
Jun. 30, 2017
USD ($)
Jan. 01, 2017
USD ($)
ft²
Related Party Transaction [Line Items]                            
Payments to acquire investments | $                       $ 1,000,000 $ 3,000,000  
Zebra                            
Related Party Transaction [Line Items]                            
Stock ownership percentage                       29.00%    
Equity method investment, ownership percentage                   29.00%   29.00%    
Neovasc                            
Related Party Transaction [Line Items]                            
Equity method investment, ownership percentage                   6.00%   6.00%    
Additional investment in equity method investment | $       $ 3,000,000                    
Number of shares into which warrants may be converted (in shares)                   2,900,000   2,900,000    
ChromaDex Corporation                            
Related Party Transaction [Line Items]                            
Ownership percentage                   0.00%   0.00%    
MabVax                            
Related Party Transaction [Line Items]                            
Ownership percentage                   2.00%   2.00%    
Payments to acquire investments | $         $ 100,000 $ 500,000                
COCP                            
Related Party Transaction [Line Items]                            
Equity method investment, ownership percentage                   9.00%   9.00%    
Additional investment in equity method investment | $             $ 1,000,000   $ 2,000,000          
Number of shares into which warrants may be converted (in shares)                   33,000   33,000    
NIMS                            
Related Party Transaction [Line Items]                            
Ownership percentage                   1.00%   1.00%    
BioCardia, Inc.                            
Related Party Transaction [Line Items]                            
Equity method investment, ownership percentage                   5.00%   5.00%    
Ownership percentage                   5.00%   5.00%    
Number of shares into which warrants may be converted (in shares)                   400,000   400,000    
InCellDx, Inc                            
Related Party Transaction [Line Items]                            
Equity method investment, ownership percentage                   29.00%   29.00%    
Number of shares into which warrants may be converted (in shares)                   700,000   700,000    
Frost Real Estate Holdings LLC                            
Related Party Transaction [Line Items]                            
Area of real estate property (in square feet) | ft²                           29,500
Lease payments per month in first year | $                           $ 81,000
Lease payments per month in third year | $                           $ 86,000
Reimbursement Of Travel Expense | Dr Frost                            
Related Party Transaction [Line Items]                            
Reimbursement paid to related party for travel | $                   $ 61,000 $ 121,000 $ 140,000 $ 141,000  
Common Stock | Neovasc                            
Related Party Transaction [Line Items]                            
Equity method investment, additional investment in period (in shares)       2,054,794                    
Common Stock | COCP                            
Related Party Transaction [Line Items]                            
Equity method investment, additional investment in period (in shares)             138,889   162,602          
Series G Preferred Stock | MabVax                            
Related Party Transaction [Line Items]                            
Available-for-sale investment, additional investment in period (in shares)         50,714                  
Series L Preferred Stock | MabVax                            
Related Party Transaction [Line Items]                            
Available-for-sale investment, additional investment in period (in shares)           1,667                
Series I Preferred Stock | MabVax                            
Related Party Transaction [Line Items]                            
Available-for-sale investment, additional investment in period (in shares)           107,607                
Museum of Science, Inc | Dr Frost and Mr Pfenniger                            
Related Party Transaction [Line Items]                            
Related party future contribution | $               $ 1,000,000            
Related party future contribution term               4 years            
Convertible Debt | COCP                            
Related Party Transaction [Line Items]                            
Additional investment in equity method investment | $     $ 1,000,000                      
Convertible Debt | Common Stock | COCP                            
Related Party Transaction [Line Items]                            
Shares received after conversion (in shares) 538,544                          
5% Convertible Notes | Convertible Debt                            
Related Party Transaction [Line Items]                            
Debt face amount | $     $ 55,000,000.0                      
Series A Warrant | Neovasc                            
Related Party Transaction [Line Items]                            
Number of shares into which warrants may be converted (in shares)       2,054,794                    
Series B Warrant | Neovasc                            
Related Party Transaction [Line Items]                            
Number of shares into which warrants may be converted (in shares)       2,054,794                    
Shares received upon exercise of warrant (in shares)   106,909,044                        
Series C Warrant | Neovasc                            
Related Party Transaction [Line Items]                            
Number of shares into which warrants may be converted (in shares)       822,192