Quarterly report pursuant to Section 13 or 15(d)

Debt - Narrative (Details)

v3.21.1
Debt - Narrative (Details)
1 Months Ended 3 Months Ended 12 Months Ended 48 Months Ended
Feb. 25, 2020
USD ($)
Jan. 30, 2013
USD ($)
Feb. 28, 2019
USD ($)
day
$ / shares
shares
Feb. 28, 2018
USD ($)
$ / shares
Nov. 30, 2015
USD ($)
Jan. 31, 2013
Mar. 31, 2021
USD ($)
institution
shares
Dec. 31, 2020
USD ($)
institution
shares
Dec. 31, 2016
USD ($)
shares
Jan. 01, 2021
USD ($)
Feb. 01, 2019
USD ($)
Debt Instrument [Line Items]                      
Credit line capacity             $ 105,795,000        
Remaining principal             246,517,000 $ 251,205,000      
Goodwill             $ 676,162,000 $ 680,602,000   $ 718,625,000  
Number of financial institutions | institution             11 11      
BioReference                      
Debt Instrument [Line Items]                      
Net assets             $ 1,077,100,000        
Goodwill             434,800,000        
Intangible assets             $ 322,000,000.0        
OPKO Health Europe                      
Debt Instrument [Line Items]                      
Weighted average interest rate             2.80% 2.90%      
Minimum | OPKO Health Europe                      
Debt Instrument [Line Items]                      
Variable interest rates             0.70%        
Maximum | OPKO Health Europe                      
Debt Instrument [Line Items]                      
Variable interest rates             3.80%        
Line of Credit                      
Debt Instrument [Line Items]                      
Remaining principal             $ 16,093,000 $ 15,897,000      
Weighted average interest rate             5.50% 4.90%      
Convertible Debt                      
Debt Instrument [Line Items]                      
Interest rate on notes payable     4.50%                
Convertible Debt | Convertible Senior Notes Due 2025                      
Debt Instrument [Line Items]                      
Debt face amount     $ 200,000,000.0                
Debt instrument, conversion ratio     0.2367424                
Conversion price per share (in dollars per share) | $ / shares     $ 4.22                
Shares issuable under debt agreement (in shares) | shares     30,000,000                
Shares issued on converted debt (in shares) | shares             29,250,000 29,250,000      
Proceeds one-time nominal fee             $ 300,000        
Equity component of convertible debt     $ 52,600,000                
Effective interest rate             11.20%        
Remaining principal             $ 158,278,000 $ 156,163,000      
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one                      
Debt Instrument [Line Items]                      
Convertible debt, threshold percentage of stock price trigger     130.00%                
Equivalent redemption price     100.00%                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one | Minimum                      
Debt Instrument [Line Items]                      
Number of trading days | day     20                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one | Maximum                      
Debt Instrument [Line Items]                      
Number of consecutive trading days applicable conversion price | day     30                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two                      
Debt Instrument [Line Items]                      
Convertible debt, threshold percentage of stock price trigger     98.00%                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two | Minimum                      
Debt Instrument [Line Items]                      
Number of trading days | day     5                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two | Maximum                      
Debt Instrument [Line Items]                      
Number of consecutive trading days applicable conversion price | day     5                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three                      
Debt Instrument [Line Items]                      
Convertible debt, threshold percentage of stock price trigger     130.00%                
Equivalent redemption price     100.00%                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three | Minimum                      
Debt Instrument [Line Items]                      
Number of trading days | day     20                
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three | Maximum                      
Debt Instrument [Line Items]                      
Number of consecutive trading days applicable conversion price | day     30                
Convertible Debt | 5% Convertible Notes                      
Debt Instrument [Line Items]                      
Interest rate on notes payable       5.00%              
Debt face amount       $ 55,000,000.0              
Conversion price per share (in dollars per share) | $ / shares       $ 5.00              
Debt instrument, term       5 years              
Minimum conversion notice       30 days              
Maximum conversion notice       60 days              
Remaining principal             63,453,000 62,776,000      
Convertible Debt | Notes Due February 1, 2033                      
Debt Instrument [Line Items]                      
Converted debt amount                 $ 143,200,000    
Senior Notes                      
Debt Instrument [Line Items]                      
Remaining principal             158,278,000 156,163,000      
Senior Notes | Notes Due February 1, 2033                      
Debt Instrument [Line Items]                      
Interest rate on notes payable   3.00%                  
Debt face amount   $ 175,000,000.0                  
Equivalent redemption price   100.00%                  
Notes | Notes Due February 1, 2033                      
Debt Instrument [Line Items]                      
Equivalent redemption price           100.00%          
Debt repurchase amount                     $ 28,800,000
Remaining principal             3,050,000 3,050,000     $ 3,000,000.0
Line of Credit | Unsecured Debt                      
Debt Instrument [Line Items]                      
Credit line capacity $ 100,000,000                    
Interest rate on notes payable 11.00%                    
Revolving Credit Facility | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Credit line capacity         $ 75,000,000.0            
Commitment fee (as a percent) 0.25%                    
Remaining principal             0 7,057,000      
Remaining borrowing capacity             64,700,000        
Commitment fee percentage         0.25%            
Long-term line of credit, noncurrent             $ 0 $ 7,100,000      
Swingline | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Credit line capacity         $ 20,000,000.0            
Letter of Credit | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Credit line capacity         $ 20,000,000.0            
LIBOR | Revolving Credit Facility | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Basis spread on variable rate         2.50%            
LIBOR, First 12 Months | Revolving Credit Facility | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Basis spread on variable rate         0.35%            
LIBOR Thereafter | Revolving Credit Facility | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Basis spread on variable rate         0.50%            
LIBOR, First 12 Months, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Basis spread on variable rate         1.35%            
LIBOR, Thereafter, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                      
Debt Instrument [Line Items]                      
Basis spread on variable rate         1.50%            
Common Stock | Convertible Debt | Notes Due February 1, 2033                      
Debt Instrument [Line Items]                      
Shares issued on converted debt (in shares) | shares                 21,539,873