Quarterly report pursuant to Section 13 or 15(d)


COVER PAGE - shares
3 Months Ended
Mar. 31, 2023
Apr. 27, 2023
Cover [Abstract]    
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Mar. 31, 2023  
Document Transition Report false  
Entity File Number 001-33528  
Entity Registrant Name OPKO Health, Inc.  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 75-2402409  
Entity Address, Address Line One 4400 Biscayne Blvd.  
Entity Address, City or Town Miami  
Entity Address, State or Province FL  
Entity Address, Postal Zip Code 33137  
City Area Code (305)  
Local Phone Number 575-4100  
Title of 12(b) Security Common Stock, par value $0.01 per share  
Trading Symbol OPK  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Large Accelerated Filer  
Entity Small Business false  
Emerging Growth Company false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding (in shares)   772,650,812
Entity Central Index Key 0000944809  
Amendment Flag false  
Document Fiscal Year Focus 2023  
Document Fiscal Period Focus Q1  
Current Fiscal Year End Date --12-31