Quarterly report pursuant to Section 13 or 15(d)

Debt - Narrative (Details)

v3.21.2
Debt - Narrative (Details)
1 Months Ended 6 Months Ended 12 Months Ended 48 Months Ended
Feb. 25, 2020
USD ($)
Jan. 30, 2013
USD ($)
May 31, 2021
USD ($)
shares
Feb. 28, 2019
USD ($)
day
$ / shares
shares
Feb. 28, 2018
USD ($)
$ / shares
Nov. 30, 2015
USD ($)
Jan. 31, 2013
Jun. 30, 2021
USD ($)
institution
shares
Jun. 30, 2020
USD ($)
Dec. 31, 2020
USD ($)
institution
shares
Dec. 31, 2016
USD ($)
shares
Jan. 01, 2021
USD ($)
Feb. 01, 2019
USD ($)
Debt Instrument [Line Items]                          
Credit line capacity               $ 106,257,000          
Amounts outstanding under line of credit               16,197,000   $ 22,954,000      
Converted debt amount               68,775,000 $ 0        
Loss on conversion of the 2025 Notes               11,111,000 $ 0        
Remaining principal               205,676,000   251,205,000      
Goodwill               $ 677,360,000   $ 680,602,000   $ 718,625,000  
Number of financial institutions | institution               11   11      
BioReference                          
Debt Instrument [Line Items]                          
Net assets               $ 1,095,700,000          
Goodwill               434,800,000          
Intangible assets               $ 314,400,000          
OPKO Health Europe                          
Debt Instrument [Line Items]                          
Weighted average interest rate               2.70%   2.90%      
Minimum | OPKO Health Europe                          
Debt Instrument [Line Items]                          
Variable interest rates               0.70%          
Maximum | OPKO Health Europe                          
Debt Instrument [Line Items]                          
Variable interest rates               3.80%          
Line of Credit                          
Debt Instrument [Line Items]                          
Remaining principal               $ 16,197,000   $ 15,897,000      
Weighted average interest rate               5.40%   4.90%      
Convertible Debt                          
Debt Instrument [Line Items]                          
Interest rate on notes payable       4.50%                  
Convertible Debt | Convertible Senior Notes Due 2025                          
Debt Instrument [Line Items]                          
Debt face amount       $ 200,000,000.0                  
Debt instrument, conversion ratio       0.2367424                  
Conversion price per share (in dollars per share) | $ / shares       $ 4.22                  
Converted debt amount     $ 55,400,000                    
Shares issued on converted debt (in shares) | shares     19,051,270         21,144,825   29,250,000      
Loss on conversion of the 2025 Notes     $ 11,100,000                    
Shares issuable under debt agreement (in shares) | shares       30,000,000                  
Decrease in shares issuable under debt agreement (in shares) | shares     8,105,175                    
Proceeds one-time nominal fee               $ 300,000          
Equity component of convertible debt       $ 52,600,000                  
Effective interest rate               11.20%          
Remaining principal               $ 116,009,000   $ 156,163,000      
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one                          
Debt Instrument [Line Items]                          
Convertible debt, threshold percentage of stock price trigger       130.00%                  
Equivalent redemption price       100.00%                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one | Minimum                          
Debt Instrument [Line Items]                          
Number of trading days | day       20                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period one | Maximum                          
Debt Instrument [Line Items]                          
Number of consecutive trading days applicable conversion price | day       30                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two                          
Debt Instrument [Line Items]                          
Convertible debt, threshold percentage of stock price trigger       98.00%                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two | Minimum                          
Debt Instrument [Line Items]                          
Number of trading days | day       5                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period two | Maximum                          
Debt Instrument [Line Items]                          
Number of consecutive trading days applicable conversion price | day       5                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three                          
Debt Instrument [Line Items]                          
Convertible debt, threshold percentage of stock price trigger       130.00%                  
Equivalent redemption price       100.00%                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three | Minimum                          
Debt Instrument [Line Items]                          
Number of trading days | day       20                  
Convertible Debt | Convertible Senior Notes Due 2025 | Redemption period three | Maximum                          
Debt Instrument [Line Items]                          
Number of consecutive trading days applicable conversion price | day       30                  
Convertible Debt | 5% Convertible Notes                          
Debt Instrument [Line Items]                          
Debt face amount         $ 55,000,000.0                
Interest rate on notes payable         5.00%                
Conversion price per share (in dollars per share) | $ / shares         $ 5.00                
Debt instrument, term         5 years                
Minimum conversion notice         30 days                
Maximum conversion notice         60 days                
Remaining principal               64,139,000   62,776,000      
Convertible Debt | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Converted debt amount                     $ 143,200,000    
Senior Notes                          
Debt Instrument [Line Items]                          
Remaining principal               116,009,000   156,163,000      
Senior Notes | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Debt face amount   $ 175,000,000.0                      
Interest rate on notes payable   3.00%                      
Equivalent redemption price   100.00%                      
Notes | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Equivalent redemption price             100.00%            
Debt repurchase amount                         $ 28,800,000
Remaining principal               3,050,000   3,050,000     $ 3,000,000.0
Line of Credit | Unsecured Debt                          
Debt Instrument [Line Items]                          
Credit line capacity $ 100,000,000                        
Amounts outstanding under line of credit               0          
Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Credit line capacity           $ 75,000,000.0              
Commitment fee (as a percent) 0.25%                        
Remaining principal               0   7,057,000      
Remaining borrowing capacity               64,300,000          
Commitment fee percentage           0.25%              
Long-term line of credit, noncurrent               $ 0   $ 7,100,000      
Swingline | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Credit line capacity           $ 20,000,000.0              
Letter of Credit | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Credit line capacity           $ 20,000,000.0              
LIBOR | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Basis spread on variable rate           2.50%              
LIBOR, First 12 Months | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Basis spread on variable rate           0.35%              
LIBOR Thereafter | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Basis spread on variable rate           0.50%              
LIBOR, First 12 Months, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Basis spread on variable rate           1.35%              
LIBOR, Thereafter, Adjusted for Eurocurrency Liabilities | Revolving Credit Facility | Line of Credit | New Credit Agreement                          
Debt Instrument [Line Items]                          
Basis spread on variable rate           1.50%              
Common Stock | Convertible Debt | Notes Due February 1, 2033                          
Debt Instrument [Line Items]                          
Shares issued on converted debt (in shares) | shares                     21,539,873