OPKO Health, Inc. Annual report pursuant to Section 13 and 15(d)

Derivative Contracts (Details 1) - Not Designated as Hedging Instrument - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Derivative Instruments, Gain (Loss) [Line Items]
Total	$ (39,083)	$ (10,632)	$ (45,942)
Common stock options/warrants
Derivative Instruments, Gain (Loss) [Line Items]
Total	(2,854)	1,193	6,544
2033 Senior Notes
Derivative Instruments, Gain (Loss) [Line Items]
Total	(36,588)	(12,213)	(52,742)
Forward contracts
Derivative Instruments, Gain (Loss) [Line Items]
Total	$ 359	$ 388	$ 256