Annual report pursuant to Section 13 and 15(d)

Acquisitions, Investments, and Licenses - Available for Sale Investments Narrative (Details)

v3.3.1.900
Acquisitions, Investments, and Licenses - Available for Sale Investments Narrative (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Investment [Line Items]      
Fair value $ 3,615 $ 5,758  
Available for sale investments, fair value 3,615    
Gain (loss) on sale of investments $ (7,091) (167) $ 29,881
Rxi      
Investment [Line Items]      
Available-for-sale investments, ownership percentage 3.00%    
Fair value $ 900    
Other Income (Expense), Net      
Investment [Line Items]      
Gain (loss) on sale of investments 0 $ 1,300 $ 29,900
Other Income (Expense), Net | Rxi      
Investment [Line Items]      
Other-than-temporary impairment charge $ 7,300    
Chromadex Corporation      
Investment [Line Items]      
Available-for-sale investments, ownership percentage 2.00%    
ARNO      
Investment [Line Items]      
Available-for-sale investments, ownership percentage 4.00%    
Available for sale investments, fair value $ 600    
ARNO | Other Income (Expense), Net      
Investment [Line Items]      
Impairment charge on available-for-sale investments $ 1,400    
MabVax      
Investment [Line Items]      
Available-for-sale investments, ownership percentage 1.00%