OPKO Health, Inc. Annual report pursuant to Section 13 and 15(d)

Employee Benefit Plans (Details)

Employee Benefit Plans (Details) - USD ($) $ in Thousands	12 Months Ended
Employee Benefit Plans (Details) - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
OPKO Health Savings and Retirement Plan
Defined Contribution Plan Disclosure [Line Items]
Maximum annual contributions per employee, percent of compensation	100.00%
Employer matching contribution, percent of employee contribution	100.00%
Company's matching discretion on employee contributions to the Plan	4.00%
Employer discretionary contribution amount	$ 800	$ 600	$ 500
Bio-Reference Laboratories, Inc. 401(k) Profit-Sharing Plan
Defined Contribution Plan Disclosure [Line Items]
Maximum annual contributions per employee, percent of compensation	60.00%
Employer matching contribution, percent of employee contribution	100.00%
Company's matching discretion on employee contributions to the Plan	3.00%
Maximum annual company match per employee	$ 1
Employer discretionary contribution amount	$ 1,500
GeneDx, Inc. 401(k) Profit-Sharing Plan
Defined Contribution Plan Disclosure [Line Items]
Maximum annual contributions per employee, percent of compensation	100.00%
Employer discretionary contribution amount	$ 800
First Tier \| GeneDx, Inc. 401(k) Profit-Sharing Plan
Defined Contribution Plan Disclosure [Line Items]
Employer matching contribution, percent of employee contribution	100.00%
Company's matching discretion on employee contributions to the Plan	3.00%
Second Tier \| GeneDx, Inc. 401(k) Profit-Sharing Plan
Defined Contribution Plan Disclosure [Line Items]
Employer matching contribution, percent of employee contribution	50.00%
Company's matching discretion on employee contributions to the Plan	2.00%